4-[3-(trifluoromethyl)phenyl]piperazin-1-ium
N-(Alpha,Alpha,Alpha-Trifluoro-m-tolyl)piperazine
CAS: 15532-75-9
Molecular Formula: C11H14F3N2
4-[3-(trifluoromethyl)phenyl]piperazin-1-ium - Names and Identifiers
| Name | N-(Alpha,Alpha,Alpha-Trifluoro-m-tolyl)piperazine |
| Synonyms | 3-(1-Piperazino)benzotrifluoride Trifluoromethyl phenyl piperazine n-3-Triflouromethylphenyl piperazine 1-(3-Trifluoromethyl)phenylpiperazine N-(3-Trifluoromethylphenyl)piperazine 1-(3-Trifluoromethylphenyl)piperazine 1-(3-(trifluoromethyl)phenyl)piperazine 1-[3-(Trifluoromethyl)phenyl]piperazine 4-[3-(trifluoromethyl)phenyl]piperazin-1-ium N-(Alpha,Alpha,Alpha-Trifluoro-m-tolyl)piperazine 3-(1-Piperazino)benzotrifluoride~N-(alpha,alpha,alpha-Trifluoro-m-tolyl)piperazine |
| CAS | 15532-75-9 |
| EINECS | 239-574-4 |
| InChI | InChI=1/C11H13F3N2/c12-11(13,14)9-2-1-3-10(8-9)16-6-4-15-5-7-16/h1-3,8,15H,4-7H2/p+1 |
4-[3-(trifluoromethyl)phenyl]piperazin-1-ium - Physico-chemical Properties
| Molecular Formula | C11H14F3N2 |
| Molar Mass | 231.237 |
| Boling Point | 305.9°C at 760 mmHg |
| Flash Point | 138.8°C |
| Vapor Presure | 0.000797mmHg at 25°C |
4-[3-(trifluoromethyl)phenyl]piperazin-1-ium - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | R36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. |
4-[3-(trifluoromethyl)phenyl]piperazin-1-ium - Introduction
N-(Alpha,Alpha,Alpha-Trifluoro-m-tolyl)piperazine is an organic compound with the chemical formula C12H9F3N, often abbreviated as TFMPP. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
N-(Alpha,Alpha,Alpha-Trifluoro-m-tolyl)piperazine is a white solid with a distinctive odor. It has a melting point between 100 and 102 degrees Celsius and can be dissolved in organic solvents such as ether, chloroform and ethanol.
Use:
TFMPP is a research compound that is used as a central nervous system stimulator in laboratory animal behavioral and pharmacological studies.
Method:
TFMPP can be prepared by a variety of synthetic routes. One commonly used method of preparation is the Boro substitution reaction of piperazine with 3-fluoromethylphenylboronic acid to produce N-(Alpha,Alpha,Alpha-Trifluoro-m-tolyl)piperazine.
Safety Information:
The toxicity and safety studies of TFMPP are relatively limited, so there is a lack of adequate safety evaluation. However, as a laboratory compound, appropriate handling measures should be taken. Contact with skin should be avoided and appropriate protective clothing and gloves should be worn during use. Avoid inhalation or ingestion and avoid contact with eyes. During use, it should be operated in a well-ventilated laboratory environment and follow relevant safe operating procedures and laboratory regulations.
It should be emphasized that TFMPP is a regulated substance and may be legally restricted in some countries for scientific research and laboratory use only. Be sure to understand and comply with local laws and regulations before use.
Nature:
N-(Alpha,Alpha,Alpha-Trifluoro-m-tolyl)piperazine is a white solid with a distinctive odor. It has a melting point between 100 and 102 degrees Celsius and can be dissolved in organic solvents such as ether, chloroform and ethanol.
Use:
TFMPP is a research compound that is used as a central nervous system stimulator in laboratory animal behavioral and pharmacological studies.
Method:
TFMPP can be prepared by a variety of synthetic routes. One commonly used method of preparation is the Boro substitution reaction of piperazine with 3-fluoromethylphenylboronic acid to produce N-(Alpha,Alpha,Alpha-Trifluoro-m-tolyl)piperazine.
Safety Information:
The toxicity and safety studies of TFMPP are relatively limited, so there is a lack of adequate safety evaluation. However, as a laboratory compound, appropriate handling measures should be taken. Contact with skin should be avoided and appropriate protective clothing and gloves should be worn during use. Avoid inhalation or ingestion and avoid contact with eyes. During use, it should be operated in a well-ventilated laboratory environment and follow relevant safe operating procedures and laboratory regulations.
It should be emphasized that TFMPP is a regulated substance and may be legally restricted in some countries for scientific research and laboratory use only. Be sure to understand and comply with local laws and regulations before use.
Last Update：2024-04-10 22:29:15